Innovations in Oncology Q2 2023
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Ambitious goals inspire a recently established digital cancer research centre
A digital research centre is partnering with patients and industry to deliver cancer research supported by cutting-edge data science and AI technology. The University of Limerick Digital Cancer Research Centre is a growing research centre of excellence, launched in September 2021. The centre has ambitious goals and has attracted almost EUR6 million in funding in...
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Looking to our immune system: promising advances in cellular immunotherapies
Experts say that ongoing trials surrounding CAR-T and NK cell immunotherapies have the potential to revolutionise cancer care. Chimeric antigen receptor T-cell (CAR-T) therapy is a form of cellular immunotherapy known as adoptive cell transfer, targeting tumour-associated antigens in cancer cells. CAR-T cells are typically developed to recognise and attack a patient’s harmful cancer cells....
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Digital health: the next frontier in the global fight against cancer
With one in six deaths still caused by cancer, experts are searching for new digital health innovations that could one day turn the tide in the fight against it. Many notable innovations have recently emerged in oncology, including CAR-T cell therapy, liquid biopsies and CRISPR-based treatment — most stemming from biological science fields such as...
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Barriers to accessing a successful targeted liver cancer treatment within Irish healthcare system
SIRT is routinely used in the USA, UK and throughout Europe for the treatment of many liver tumours. In Ireland, however, there is no national funding agreement for SIRT, leaving patients with fewer treatment prospects. Selective internal radiation therapy (SIRT) is a targeted treatment for some liver tumours that delivers millions of tiny radioactive beads,...
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Barrett’s oesophagus can progress into oesophageal cancer if not managed
A small number of people (less than 1%) with Barrett’s oesophagus can develop oesophageal cancer. Therefore, this condition must be regularly monitored to ensure cancer prevention. The National Barrett’s Oesophagus Registry and Biobank were established in 2009 to meet the Oesophageal Cancer Fund’s aim of preventing Oesophageal Cancer through early detection. Barrett’s oesophagus can pose cancer...
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Around 2,562 people each year are diagnosed with bowel cancer in Ireland
Rates of colorectal cancer in under-50s have almost doubled in just 25 years, highlighting the need for those under the screening age of 60 not to dismiss symptoms. In Ireland, around 2,562 people each year develop bowel cancer, also known as colon, rectal or colorectal cancer. Bowel cancer is the third leading cause of cancer...
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Cancer projections and common risk factors to avoid
Due to population growth and ageing, it is expected that the number of cancer cases will increase significantly, with the most optimistic projections being 50% higher by 2045. The National Cancer Registry Ireland (NCRI) collects information on all cancers in Ireland since 1994. This information is analysed to produce statistics about cancer every year. In...
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Multidisciplinary approach to cancer survivorship can help more patients
As cancer patients are often able to live longer with modern interventions, a multidisciplinary team in Galway are addressing survivorship, recovery and treatment to ensure the best possible quality of life. The prognosis for breast cancer patients in Ireland has improved significantly since the introduction of the breast cancer screening programme and improved therapies, including...
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Potential for improved treatment of aggressive types of prostate cancer
An ongoing trial known as ‘Darolutamide Augments Standard Therapy for Localised Very High-Risk Cancer of the Prostate’ (DASL-HiCaP) can potentially benefit men with aggressive prostate cancer types in addition to standard treatment. DASL-HiCaP is a prostate cancer trial for patients with aggressive types of prostate cancer that remain confined to the prostate area. The purpose...
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Enabling personalised medicine for cancer patients across the island through digital revolution
Biology and medicine are morphing into data-driven sciences. The dream of personalised medicine — finding the right medicine for the right patient at the right time — is coming into reach. This digital transformation is particularly visible in oncology, where genome sequencing in the clinic has shown the importance of data analysis in enabling clinical...
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